Micro-CT in Pharmacology

Micro-CT is a relatively new approach to imaging the internal structure of solid dosage forms. It helps to understand changes in structural features during manufacturing, handling and storage of solid dosage forms.

Some evaluations performed by Micro-CT are:

• Micro carcking in tablets
• Elucidation of structural features
• Chemical mapping
• Homogeneity
• Porosity
• Counterfeit product detection
• Compaction studies
• Seal integrity in packaging
• The gap between the inner core and the outer core of the press-coated tablet